Researchers model herpes protein in 3D, identify its action

Scientists in the UK have reported using 3D imaging to uncover a critical protein mechanism in the interaction between the herpes virus and human cells.

They utilized nuclear magnetic resonance (NMR) spectroscopy, a technology related to medical magnetic resonance imaging, to visualize a particular viral protein as it piggybacked on a human protein, according to a study published in the journal PLoS Pathogens.

A herpes protein called ICP27 was imaged while connecting to a human transcription protein, which is responsible for copying DNA.

It is this interaction, along with several others, that forces human cells to make copies of herpes viruses.

Using the NMR imaging, the team said they were able to model the protein's connection and thus better understand how herpes viruses take control of cellular machinery.

Currently, herpes has no cure. Treatment options consist primarily of managing symptoms, which include painful sores, swollen glands and genital discharge.

Individuals who suspect that they have contracted herpes or another sexually transmitted disease may consider using an online testing service to diagnose their symptoms.