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Antidepressants may improve patients' adherence to hepatitis C medications

Christopher Lynch, MD Apr. 14, 2011

Due to medical advancements, many individuals who suffer from hepatitis C have been able to reduce their symptoms and increase their chances of recovering from the disease. However, some patients who fail to adhere to their drug regimens do not show health improvements.

The findings of a recent study conducted by Medco Health Solutions indicate that people who receive antidepressants in combination with their hepatitis C medications are more likely to follow their drug regimens than those who only take the latter.

The researchers explained that interferon medications that are commonly used to treat hepatitis C may cause mood-related side effects.

Findings showed that 40 percent of infected participants who had been prescribed interferon did not comply with the drug's dosage instructions. However, among hepatitis C-positive subjects who received antidepressants along with their disease-related medications, the results indicated that more than 68 percent adhered to their treatment regimens.

"These findings point to the need to proactively screen patients on interferon for depression and make sure that those who show signs of depression receive the proper interventions," lead researcher Mary Cassler said.

The scientists noted that individuals who fail to take their hepatitis C medications often require additional treatment later on.

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